Does it affect me?
Article 45 of the CLP Regulation defines importers and downstream users who place hazardous mixtures on the market as responsible parties. In all cases, the obligation falls on the legal entity established in the European Union that is appropriate within the supply chain, which means that a supplier of the mixture not domiciled in the EU cannot replace the responsible person who is domiciled in the European Union. It is also important to note that compliance with the notification obligation is a prerequisite for placing the mixture on the market; this may be significant in cases where neither the importer nor the downstream user is the one placing the product on the market.
Information reviewed in September 2026.
Reporting requirements to poison control centers must be analyzed based on the mixture’s classification, the company’s role in the supply chain, the intended use, and the countries in which the product is marketed.
More information about the different actors in the supply chain and the activities leading to the filing obligation can be found in the Guidance on Annex VIII.
For which mixes do I have to submit information?
The obligation applies to marketed mixtures classified in relation to human health or physical hazards.
Please note that biocides and plant protection products are within the scope of this obligation and that the reporting requirements apply in addition to other obligations under the Biocides Regulation and the Plant Protection Products Regulation.
Which mixtures are exempt?
The reporting requirement does not apply to mixtures considered hazardous only because of environmental hazards. Mixtures exempted from reporting requirements include the following:
Required Information and Documentation
When a PCN notification is required, harmonized information on the mixture—including its composition, classification and labeling, toxicological data, commercial information, and product identification—must typically be prepared. It may also be necessary to generate and submit the Unique Formula Identifier (UFI).
The safety data sheet, formulation, CLP classification, labeling, and supplier information must be reviewed thoroughly before preparing the notification.
Do you need to review a mix?
ADR Area Advisers can help you determine whether your mixtures require a PCN notification, prepare the necessary technical documentation, generate UFI codes, and verify consistency between classification, labeling, safety data sheets, and notifications.
Contact ADR Area Advisers to have your case evaluated.
